To do so, they would need to ignore the patents on drugs and produce generics within the country (using a compulsory license), or import them from abroad. Legal claims against the pharmaceutical industry have varied widely over the past two decades, including Medicare and Medicaid fraud , off-label promotion, and inadequate manufacturing practices. Every major company selling the antipsychotics — Bristol-Myers Squibb , Eli Lilly , Pfizer , AstraZeneca and Johnson & Johnson — has either settled recent government cases, under the False Claims Act, for hundreds of millions of dollars or is currently under investigation for possible health care fraud.

These include: Good Manufacturing Practice (GMP) Violations, Off Label Marketing, Best Price Fraud, CME Fraud, Medicaid Price Reporting, and Manufactured Compound Drugs. A 2012 report by the President’s Council of Advisors on Science and Technology made several key recommendations to reduce regulatory burdens to new drug development, including 1) expanding the FDA’s use of accelerated approval processes, 2) creating an expedited approval pathway for drugs intended for use in narrowly defined populations, and 3) undertaking pilot projects designed to evaluate the feasibility of a new, adaptive drug approval process. In the first quarter of 2017, the health products and pharmaceutical industry spent $78 million on lobbying member of the United States Congress.

The expectation is that relationship between doctors and Pharmaceutical industry will become fully transparent. It has been argued that the design of the Diagnostic and Statistical Manual of Mental Disorders and the expansion of the criteria represents an increasing medicalization of human nature, or “ disease mongering “, driven by drug company influence on psychiatry. Retail sales of prescription drugs jumped 250 percent from $72 billion to $250 billion, while the average price of prescriptions more than doubled from $30 to $68.

Often the owner of the branded drug will introduce a generic version before the patent expires in order to get a head start in the generic market. When the patent protection for the drug expires, a generic drug is usually developed and sold by a competing company. In 2011, global spending on prescription drugs topped $954 billion, even as growth slowed somewhat in Europe and North America.

In England and Wales NICE decides whether and in what circumstances drugs and technologies will be made available by the NHS, whilst similar arrangements exist with the Scottish Medicines Consortium in Scotland, and the Pharmaceutical Benefits Advisory Committee in Australia. In contrast to this viewpoint, an article and associated editorial in the New England Journal of Medicine in May 2015 emphasized the importance of pharmaceutical industry-physician interactions for the development of novel treatments, and argued that moral outrage over industry malfeasance had unjustifiably led many to overemphasize the problems created by financial conflicts of interest.
http://www.medicinenet.com/script/main/art.asp?articlekey=3946
https://www.fda.gov/Drugs/DrugSafety/ucm118692.htm
https://farmatrade.eu
https://mon-tierce.fr/
https://www.health.harvard.edu/staying-healthy/do-generic-drugs-compromise-on-quality
https://pharmacy.lau.edu.lb/
https://24pilules.eu/